发明名称 FORFARANDE FOR FRAMSTELLNING AV PROSTACYKLINDERIVAT
摘要 5,9-Cyclic ethers of 9-deoxyprostaglandin-F1 alpha -type compounds of the formula <IMAGE> in which the substituents are defined in Patent Claim 1, are prepared. These compounds are obtained by converting a compound of the formula <IMAGE> into a mercury compound of the formula <IMAGE> and subsequently subjecting this latter compound to a reductive removal of mercury, resulting in the formation of the ether. The compounds which are obtained may be used as antiinflammatory agents as well as for inhibiting blood platelet aggregation in vivo or in vitro.
申请公布号 SE434266(B) 申请公布日期 1984.07.16
申请号 SE19770009477 申请日期 1977.08.23
申请人 THE UPJOHN COMPANY 发明人 R A * JOHNSON;J C * SIH
分类号 A61K31/35;A61K31/352;A61K31/555;A61K31/557;A61P7/02;A61P31/00;A61P43/00;C07C405/00;C07D307/935;C07D311/94;C07F3/14;(IPC1-7):07D311/94 主分类号 A61K31/35
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