摘要 |
<p>NEW 8 FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS. The invention relates to new 8.alpha.-oestra-1,3,5(10)-triene derivatives having the formula: in which R1 = H or a free, esterified or etherified hydroxy group; R2 = H or a free, esterified or etherified hydroxy group, with the proviso that at least one of the substituents R1 and R2 is different from H; R3 = alkyl (1-4 C) and R4 = O or (.alpha.X) (.beta.Y), in which X = H or aliphatic hydrocarbyl (1-4 C) and Y = a free, esterified or etherified hydroxy group and the enantiomers and racemic mixtures thereof, and also extends to processes for their preparation and to pharmaceutical compositions containing said new compounds.</p> |