发明名称 |
N-ACYL PEPTIDE COMPOUND, PROCESS FOR THE PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITIONS |
摘要 |
<p>N-acyl peptides of the formula: wherein R1 and R2 are each alkyl or alkenyl R3 is hydrogen, lower alkyl, hydroxy(lower)alkyl, heterocyclic(lower)alkyl or ar(lower)alkyl, wherein the aryl moiety may have hydroxy or protectod hydroxy, R4 is carboxy, esterified carboxy. carboxy(lower)alkyl or esterified carboxy(lower)alkyl, X is bond or lower alkylene; Y is lower alkylene or lower alkylldene and n is an integer of 0 or 1; and pharmaceutically acceptable salts, have anticomplemantary activity and fibrinolytic activity and may be used in the treatment of immune-complex diseases or autoimmune diseases.</p> |
申请公布号 |
CA1170599(A) |
申请公布日期 |
1984.07.10 |
申请号 |
CA19810392320 |
申请日期 |
1981.12.15 |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
UMEHARA, KAZUYOSHI;TANAKA, HIROKAZU;UCHIDA, ITSUO;KOHSAKA, MASANOBU;IMANAKA, HIROSHI;YOSHIDA, KEIZO |
分类号 |
C12P21/00;A61K38/00;A61P7/02;A61P7/04;A61P37/00;C07C67/00;C07C231/00;C07C231/02;C07C231/12;C07C233/47;C07C235/06;C07C235/08;C07C235/12;C07C235/28;C07C237/12;C07C237/22;C07K1/113;C07K1/20;C07K5/06;C07K5/062;C07K14/195;C07K14/41;C12R1/20;(IPC1-7):C12P21/02;C07C103/52;C12P13/04 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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