| 摘要 |
Title compds.(I; R1 = Cl, Br; R2 = trifluoromethyl, Cl, F; R3 = C3-5 side chain alkyl radical, cycloalkyl) useful as bronchomucolytics, were prepd. by reduction of II (R4 = acyl radical). II was obtained by reaction of III and IV or V. Thus, 3.32 g t-butylisonitrile and 4.8 g acetic acid were dropped in 50 ml anhyd. methylene chloride contg/ 3.8 g 4-amino-3,5-dichloro-benzaldehyde at room temp for 8 hr to give-acetoxy- -(4-amino-3,5-dichloro-phenyl)-N-t-butylacetamide.
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