发明名称 |
SETT ATT FRAMSTELLA NYA ARYLOXIAMINOBUTANOLER, STEREOISOMERER OCH OGIFTIGA SYRAADDITIONSSALTER DERAV |
摘要 |
Novel aryloxyaminobutanols of the general formula (I) <IMAGE> in which R represents an optionally substituted aryl group and R<1> represents an alkyl, cycloalkyl or aralkyl group, it being possible for the aryl group to be substituted, and also the stereoisomers and the non-toxic acid addition salts of these compounds, are beta-receptor blockers and have antiarrhythmic action. The compounds are prepared by reacting compounds of the general formula (III) <IMAGE> and compounds of the general formula (IV> X-R<1> (IV> in which X represents a leaving group, or reacting compounds of the general formula (III) with compounds of the general formula (V) <IMAGE> and simultaneously or subsequently reducing, and if desired reacting the resulting compounds of the general formula (I) to give their non-toxic acid addition salts or liberating them from their salts. The stereoisomers of the formula III can be used as starting materials. |
申请公布号 |
SE433935(B) |
申请公布日期 |
1984.06.25 |
申请号 |
SE19750001801 |
申请日期 |
1975.02.18 |
申请人 |
CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT |
发明人 |
1)K * HARSANYI;2)D * KORBONITS;3)E * MOLNAR;4)J * SZEGI |
分类号 |
A61K31/135;A61K;A61K31/13;A61K31/138;A61P9/06;A61P25/02;C07C;C07C67/00;C07C213/00;C07C217/30;C07C217/32;C07C217/38;(IPC1-7):07C93/06 |
主分类号 |
A61K31/135 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|