摘要 |
PURPOSE:To extract and to separate high-purity S-adenosyl-L-methionine efficiently, by freezing a mold containing S-adenosyl-L-methionine by a safe and simple process. CONSTITUTION:A yeast mold accumulating S-adenosyl-L-methionine in its body obtained by cultivating a yeast belonging to the genus Saccharomyces, etc. is collected, it is suspended in 1-100pts.wt., preferably 3-10pts.wt. water based on 1pt.wt. wet mold amount to give a suspension, which is brought into contact with an aqueous solution of a bivalent ion, frozen, the frozen substance is melted by a conventional procedure, and the mold residue is removed from the prepared melted solution by a conventional procedure. |