| 摘要 |
Derivatives of 2-azabicyclo[2.2.1]heptane of the formula I <IMAGE> in which n = 0 or 1, R denotes hydrogen, alkyl or aralkyl, R<1> denotes hydrogen or alkyl which can optionally be substituted by amino, acylamino or benzoylamino, alkenyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, aryl or partially hydrogenated aryl, each of which can be substituted by alkyl, alkoxy or halogen, or aralkyl or aroylalkyl which can both be substituted in the aryl radical as defined above, a mono- or bicyclic S- or O- and/or N-heterocycle radical or a side chain of an alpha -amino acid, R<2> denotes hydrogen, alkenyl or aralkyl, Y denotes hydrogen or hydroxyl, Z denotes hydrogen or Y and Z together denote oxygen and X denotes alkyl, alkenyl, cycloalkyl, aryl which can be mono-, di- or trisubstituted by alkyl, alkoxy, hydroxyl, halogen, nitro, amino, alkylamino, dialkylamino and/or methylenedioxy, or 3-indolyl, process for their preparation, agents containing them and their use, and 2-azabicyclo[2.2.1]heptane derivatives as intermediates, and process for their preparation. |
