| 摘要 |
PURPOSE:To prepare the titled compound in high yield and purity, economically, by reacting an aliphatic alcohol with an aliphatic secondary amine in the presence of hydrogen gas and a catalyst while keeping the reaction pressure within a specific range and the partial pressure of the secondary amine within a specific range. CONSTITUTION:Hydrogen gas and an aliphatic secondary amine are introduced into an aliphatic alcohol in the presence of a hydrogenation-dehydrogenation an aliphatic alcohol in the presence of a hydrogenation-dehydrogenation catalyst selected from Raney-copper, Raney-cobalt, etc. which is a catalyst obtained by supporting copper-chromite, copper-zinc oxide, etc. on a carrier such as alumina, carbon, etc., and the components are made to react with each other under heating, In the above process, the introduction of hydrogen gas into the reaction system is carried out under the hydrogen pressure of 6-100 atm, and the partial pressure of the secondary amine in the reaction atmosphere is adjusted to 0.001-0.4 atm when the conversion of the aliphatic alcohol is <=90% and to 0.1-0.7 atm when the conversion is >90% by controlling the feeding rate of the secondary amine to the reaction system. |
