发明名称 Substituted nitropyrazine compounds, process for their preparation and pharmaceutical compositions containing them.
摘要 2 or 6 substituted and 2,6-disubstituted derivatives of 3-nitropyrazine and processes for their preparation are disclosed. Said derivatives have an activity in increasing the sensitivity of tumor cells to radiation. Also disclosed are pharmaceutical compositions containing said derivatives as active ingredients.
申请公布号 EP0111151(A1) 申请公布日期 1984.06.20
申请号 EP19830110974 申请日期 1983.11.03
申请人 MERCK & CO. INC. 发明人 HARTMANN, GEORGE D.
分类号 C07D241/20;C07D241/16;A61K31/495;A61P43/00;C07D241/26;C07D241/28;(IPC1-7):07D241/16;07D241/26;07D241/20 主分类号 C07D241/20
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