发明名称 PROCESS FOR PREPARING ANALOGS OF PROSTACYCLIN
摘要 Compds. of the general formula I (where R1=a staright or branched alkyl residue with <=6C atoms, a straight or branched aliph. hydrocarbon residue with 3-6 C atoms, a cycloaliph. hydrocarbon residue with 3-7 C atoms, an araliph. hydrocarbon residue with 7-9 C atoms, or a physiol compatible metal, NH4, or ammonium ion derived from a primary or tertiary amine or a tetraalkylammonium ion; and R2=a cycloalkyl residue with 3-7 C atoms or a straight or branched alkyl residue with <=8 C atoms, which could also be substituted with ahlogen, an α- or α-thienyl residue, an α- or β-furyl residue, an oxyphenyl, or an α- or β-oxythienyl residue) were prepd. and tested for blood pressure-lowering activity in rats, bovine coronary artery relaxation activity, and blood platelet aggregation activity.
申请公布号 KR840000864(B1) 申请公布日期 1984.06.20
申请号 KR19800000265 申请日期 1980.01.23
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 BARTMANN WILHELM;HERCH ULRICH;KONZ ELMAR;SCHOELKENS BERNWARD
分类号 C07D307/935;(IPC1-7):C07D307/93 主分类号 C07D307/935
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