摘要 |
<p>Anthraquinones of the formula: …<CHEM>… wherein Q is a divalent moiety, A is -(CH2)nX(CH2)p-, X is selected from the group consisting of …<CHEM>… R is hydrogen or hydroxy, R1 and R2 are each individually selected from the group consisting of hydrogen, alkyl having from 1 to 4 carbon atoms and monohydroxyalkyl having from 2 to 4 carbon atoms, wherein the carbon atom alpha to the nitrogen atom may not bear a hydroxyl group, and R3 is hydrogen or lower alkyl (C1-C3); and pharmaceutically acceptable acid-addition salts thereof, useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.</p> |