| 摘要 |
<p>Dl-1-(or 3-) carbamoyl-2-hydroxy-5,6,7,8- tetrahydronaphthalenes of the formula
<CHEM>
wherein:
one of R and R<1> is H and the other is CONH2,
R<2> and R<3> are individually H, methyl, ethyl or n-propyl, and
pharmaceutically-acceptable acid addition salts thereof.
<??>The compounds are prepared by amidating the 1-(or 3-)ester or carboxhydrizide by reducing the 6-azide, by cleaving the 2-benzyl-oxy group, or by alkylating the 6-amine.
<??>These compounds possess a dopamine- like pharmacological activity. </p> |
