| 发明名称 |
PROCESS FOR REMOVING TRITYL BLOCKING GROUPS FROM 5'-O TRITYL NUCLEOSIDES AND OLIGONUCLEOTIDES |
| 摘要 |
<p>Trityl blocking groups from 5 min -O-trityl nucleosides and oligonucleotides are removed by contacting said nucleoside or oligonucleotide with a Lewis acid. This process is especially useful in synthetic processes for producing oligonucleotides and polynucleotides because the 5 min -O-trityl groups are selectively removed without removing trityl blocking groups in 3 min -O-position.</p> |
| 申请公布号 |
EP0035255(B1) |
申请公布日期 |
1984.05.30 |
| 申请号 |
EP19810101444 |
申请日期 |
1981.02.27 |
| 申请人 |
UNIVERSITY PATENTS, INC. |
发明人 |
CARUTHERS, MARVIN H.;MATTEUCCI, MARK D. |
| 分类号 |
C07H19/06;B01J19/00;C07H19/04;C07H19/10;C07H19/16;C07H19/20;C07H21/00;C07H21/02;C07H21/04;C07H23/00;C40B40/06;C40B60/14;(IPC1-7):07H21/00;07H19/04 |
主分类号 |
C07H19/06 |
| 代理机构 |
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