| 摘要 |
NEW MATERIAL:An N-propargyl-N-acrylhydroxylamine derivative shown by the formula I (R<1> is H, alkyl, phenyl, etc.; R<2> is alkyl, or alkenyl; with the proviso that R<2> is not lower alkyl when R<1> is phenyl). EXAMPLE:N-propargyl-N-acetyl-O-methylhydroxylamine. USE:An anthelmintic. Having low toxicity to warm-blooded animals such as pig, horse, bovine, etc., and high anthelmintic activity. Capable of being administered directly, the titled derivative may be added to a feed or drinking water, etc. It may be applied at any period. PROCESS:A compound shown by the formula II is reacted with CHidenticalC.CH2X (X is Cl, Br, or I) in the presence of a deoxidizer(e.g., sodium methoxide, etc.) in a solvent such as methanol, etc. at 0-100 deg.C, to give a compound shown by the formula I . |
