发明名称 CONSTANT RELEASE RATE SOLID ORAL DOSAGE FORMULATION OF PHARMACEUTICAL COMPOUNDS HAVING A HIGH DEGREE OF WATER SOLUBILITY
摘要 The present invention provides constant order release tablets of drugs which have a high degree of water-solubility. The tablet formulations of this invention comprise: a therapeutically effective amount of a drug having a high degree of water solubility, from about 8-18 weight percent of an acrylic acid polymer; from about 8-18 weight percent of polyethylene glycol having a molecular weight of from 4000-6000; from about 2 to 9 weight percent of a hydrogenated vegetable oil; from about 0.5 to 3 weight percent of fumed silicon dioxide; from about 15 to 25 weight percent of a disintegrant; from about 20 to 40 weight percent of a diluent; and from 0.5 to 2 weight percent of a lubricant.
申请公布号 ZA8306627(B) 申请公布日期 1984.05.30
申请号 ZA19830006627 申请日期 1983.09.06
申请人 VEREX LABOR INC 发明人 DUNN JAMES MICHAEL;HAAS RONALD THOMAS
分类号 A61K9/20;A61K9/22 主分类号 A61K9/20
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