发明名称 PROCESS FOR THE PREPARATION OF 2-PENEM
摘要 <p>Compounds of the general formula: <CHEM> in which R1, R2, R3, X and 2 are as defined herein, and their pharmaceutically acceptable salts; especially those subject to the following provisos: (i) when X is S, Z is O or =NR7 (R7 being as defined herein); (ii) when X is O, Z is O, S or =NR7; (iii) when X is -CH2-, Z is =NR7; (except that when R7 is H or C1-C6 alkyl and R2 is C1-C6 alkyl, then R1 cannot be acylamino; (iv) when X is (CH2)2, Z is=NR7; and their pharmaceutically acceptable salts. These compounds are antibacterial agents which can be incorporated into pharmaceutical compositions or used as intermediates in the preparation of such agents.</p>
申请公布号 PT74356(B) 申请公布日期 1984.05.30
申请号 PT19820074356 申请日期 1982.01.29
申请人 SCHERING CORPORATION 发明人 ADRIANO AFONSO;FRANK HON
分类号 C07D499/897;A61K31/397;A61K31/40;A61K31/415;A61P31/04;C07D205/08;C07D205/09;C07D463/00;C07D477/00;C07D477/04;C07D477/22;C07D487/04;C07D499/00;C07D499/04;C07D499/06;C07D499/32;C07D499/88;C07D503/00;C07F7/18;(IPC1-7):07D499/00;07D205/08;07D471/04;07D263/00;07D235/00;07D209/00;07D205/00;07D221/00;61K31/545;61K31/43;61K31/42;61K31/40;07F7/18;07D498/04;07D487/04 主分类号 C07D499/897
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