摘要 |
<p>The invention relates to polypeptides, in particular to penta- and hexapeptides, characterized by the general formula 1:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="14" wi="87" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>or a functional derivative thereof, wherein
<UnorderedLists id="ula01" listStyle="none"><ListItem>Z represents hydrogen or NH<Sub>2</Sub>,</ListItem><ListItem>ALK<Sub>1</Sub> represents an alkylene of alkylidene group having 1-6 carbon atoms,</ListItem><ListItem>ALK<Sub>2</Sub> represents an alkylidene group having 1-6 carbon atoms, Met<Sub>x</Sub> represents the aminoacid radical Met, Met(O) or Met(0<Sub>2</Sub>) and</ListItem><ListItem>Q represents the aminoacid radical Lys or Arg, with the proviso that one of the aminoacid radicals Q and the C-terminal Phe is in the D-configuration and the other has the L-configuration.</ListItem></UnorderedLists></p> |