7 alpha -Alkoxycarbonyl-15 beta ,16 beta -methylene-4-androstenes, process for the preparation thereof, and use thereof as medicinal agents

摘要

7 alpha -Alkoxycarbonyl-15 beta ,16 beta -methylene-4-androstene compounds of Formula I <IMAGE> (I) wherein R1 is hydrogen or methyl, R2 is alkyl of 1-4 carbon atoms, X is <IMAGE> and Y is carbonyl, and the bond between the C-1 and C-2 carbon atoms is a single or double bond, or when the bond between the C-1 and C-2 carbon atoms is a single bond, X can also be <IMAGE> when Y is <IMAGE> possess valuable pharmacological properties, e.g., as aldosterone antagonists, i.e. they reverse the effect of deoxycorticosterone on the excretion of sodium and potassium.