| 摘要 |
<p>The invention discloses cyclohexyl and phenyl substituted enkephalin derivatives of the formula: <IMAGE> Where R1, R2, R4, and R8 is hydrogen or alkyl of R3 is alkylthioalkyl or alkylsulfinylalkyl, X is: <IMAGE> R5 is cyclohexylmethyl, phenylmethyl, optionally substituted by -NO2, R6 is cyclohexyl or phenyl optionally substituted by R7 and R7 is hydrogen, an alkyl ester of carboxylic acid or hydroxyalkyl and the pharmaceutically acceptable salts, which are useful as analgesic agents.</p> |
