Indole derivatives.

摘要

This invention relates to indole derivatives which have anti-cancer activity. According to the invention there is provided an indole derivative of the formula I :
<Chemistry id="chema01" num="0001"><Image id="ia01" he="16" wi="71" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>in which X is an oxygen or sulphur atom, Ra is a phenyl radical which is optionally substituted by one or two groups selected from halogen atoms and 1-6C alkyl, 1-6C alkoxy and trifluoromethyl radicals and Rb is a hydrogen atom or a 2-6C alkoxycarbonyl radical. Manufacturing processes and pharmaceutical compositions are also described.