POLYPEPTIDES USEFUL IN VACCINATION AGAINST ENTEROVIRUSES

摘要

PCT No. PCT/GB83/00254 Sec. 371 Date Jun. 8, 1984 Sec. 102(e) Date Jun. 8, 1984 PCT Filed Oct. 11, 1983 PCT Pub. No. WO84/01575 PCT Pub. Date Apr. 26, 1984.A synthetic polypeptide, suitable for use in vaccination against or diagnosis of a disease caused by an enterovirus, is an octapeptide coded for by codons 93-100 in the RNA sequence coded for the structural capsid protein VP1 for poliovirus type 3 Sabin strain or by equivalent codons of another enterovirus or is an antigenic equivalent of such an octapeptide, the numbers of the codons being counted from the 5'-terminus of the nucleotide sequence for the VP1 capsid protein.