发明名称 |
Nitroimidazole compounds and compositions useful in the treatment of acne. |
摘要 |
<p>Metronidazole retinoate and mizonidazole retinoate, with the formula (I) <CHEM> which are new compounds, are useful in the treatment of acne by topical application. Pharmaceutical compositions comprising retinoic acid or a lower alkyl ester thereof and an ester of metronidazole or mizonidazole with an acid of formula RCOOH in which R is an aliphatic residue such that RCOOH is an aliphatic acid of 3 to 10 carbon atoms, are useful for the same purpose.</p> |
申请公布号 |
EP0106926(A1) |
申请公布日期 |
1984.05.02 |
申请号 |
EP19820305740 |
申请日期 |
1982.10.28 |
申请人 |
DIOMED DEVELOPMENTS LIMITED |
发明人 |
WHITEFIELD, MARTIN;WEINSTOCK, MARCEL |
分类号 |
C07D233/95;A61K8/49;A61K8/67;A61K9/06;A61P17/00;A61Q19/00;C07D233/94;(IPC1-7):07D233/94;61K31/415 |
主分类号 |
C07D233/95 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|