| 发明名称 |
Dihydropyridines. |
| 摘要 |
<p>1,4-Dihydropyridine derivatives of the formula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="24" wi="84" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>and their pharmaceutically acceptable acid addition salts; where
<UnorderedLists id="ula01" listStyle="none"><ListItem>R is aryl or heteroaryl;</ListItem><ListItem>R<Sup>1</Sup> and R<Sup>2</Sup> are each independently C<Sub>1</Sub>-C<Sub>4</Sub> alkyl or 2-methoxyethyl; Y is -(CH<Sub>2</Sub>)<Sub>2</Sub>-, -(CH<Sub>2</Sub>)<Sub>3</Sub>-, -CH<Sub>2</Sub>CH(CH<Sub>3</Sub>)-or-CH<Sub>2</Sub>C(CH<Sub>3</Sub>)<Sub>2</Sub>-;</ListItem><ListItem>R<Sup>3</Sup> is
<Chemistry id="chema02" num="0002"><Image id="ia02" he="25" wi="84" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry><Chemistry id="chema03" num="0003"><Image id="ia03" he="28" wi="70" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry><Chemistry id="chema04" num="0004"><Image id="ia04" he="26" wi="88" file="IMGA0004.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry></ListItem></UnorderedLists></p><p>The compounds have utility as anti-ischaemic and antihypertensive agents.</p> |
| 申请公布号 |
EP0107293(A2) |
申请公布日期 |
1984.05.02 |
| 申请号 |
EP19830304955 |
申请日期 |
1983.08.26 |
| 申请人 |
PFIZER LIMITED;PFIZER CORPORATION |
发明人 |
CAMPBELL, SIMON FRASER, DR.;STUBBS, JOHN KENDRICK, DR.;CROSS, PETER EDWARD, DR. |
| 分类号 |
A61K31/4427;A61K31/455;A61K31/495;A61K31/505;A61P3/00;A61P9/08;A61P9/10;A61P9/12;C07D211/90;C07D401/12;C07D417/12;(IPC1-7):07D401/12;07D417/12;61K31/445 |
主分类号 |
A61K31/4427 |
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