发明名称 |
Hypotensive piperidine derivatives |
摘要 |
PCT No. PCT/JP79/00141 Sec. 371 Date Feb. 2, 1980 Sec. 102(e) Date Jan. 31, 1980 PCT Filed Jun. 1, 1979 PCT Pub. No. WO80/00024 PCT Pub. Date Jan. 10, 1980.The present invention relates to a novel compound represented by the general formula: <IMAGE> wherein Ar represents a naphthyl, phenyl or substituted phenyl group, Q represents <IMAGE> wherein R1 represents a hydrogen atom, or an alkyl, alkanoyl or alkoxycarbonyl group, R represents a hydrogen atom or an alkyl group, and Z represents a substituted benzimidazolinyl group; the broken line in piperidine ring means that 3,4-positions in the piperidine ring are saturated or form a double bond. Said compound and the pharmaceutically acceptable acid addition salts thereof have a hypotensive action and therefore are useful as medicine.
|
申请公布号 |
US4446141(A) |
申请公布日期 |
1984.05.01 |
申请号 |
US19800191339 |
申请日期 |
1980.02.02 |
申请人 |
NAKAMIZO, NOBUHIRO;OBASE, HIROYUKI;KUBO, KAZUHIRO;KASUYA, YUTAKA |
发明人 |
NAKAMIZO, NOBUHIRO;OBASE, HIROYUKI;KUBO, KAZUHIRO;KASUYA, YUTAKA |
分类号 |
A61K31/41;A61P9/12;C07D401/04;C07D405/14;(IPC1-7):A61K31/44 |
主分类号 |
A61K31/41 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|