摘要 |
<p>Process comprises reaction of 1-ethyl-6-fluoro-7-chloro-1,4-dihydro- 4-oxo -quinoline carboxolic acid with piperazine. The reaction is effected in an inert solvent. - The prod., 1-phenyl-6-fluoro -1,4-dihydro-4-oxo-7 -(1-piperazinyl)3-quinoline carboxylic acid, is sepd. by conventional means.</p> |