发明名称 PROCESS FOR THE DECOMPOSITION OF (+)-I-(-)-6-METHOXY-ALPHA-METHYL-2-NAPHTHALIN ACETIC ACID
摘要 <p>The subject of the invention is a process for resolving mixtures of (+)- and (-)-6-methoxy- alpha -methyl-2-naphthaleneacetic acid into the enantiomers thereof, characterized in that N-methyl-D-glucamine [=1-deoxy-1-(methylamino)-D-glucitol] is used as the resolving agent, so that the 6-methoxy- alpha -methyl-2-naphthaleneacetic acid is converted into the corresponding diastereoisomeric N-methyl-D-glucamine salt pair which, because of very different solubilities, can be separated easily and completely with high yield.</p>
申请公布号 YU173679(A) 申请公布日期 1984.04.30
申请号 YU19790001736 申请日期 1979.07.16
申请人 SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED 发明人 FELDER E.;PITRE D.;ZUTTER H.
分类号 C07C59/64;C07B31/00;C07B57/00;C07C51/00;C07C51/487;C07C51/64;C07C53/136;C07C67/00;(IPC1-7):07C63/34;61K31/19;07B20/00 主分类号 C07C59/64
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