发明名称 |
PROCESS FOR PRODUCING 7-SUBSTITUTED-3-CEPHEME-4-CARBOXYLIC ACID DERIVATIVES |
摘要 |
<p>Cephem compounds of the formula: …<CHEM>… wherein R<1> is amino or a protected amino,… R<2> is lower alkyl,… R<3> is hydrogen or lower alkyl,… R<4> is hydrogen, acyloxy(lower)alkyl, acylthio(lower)alkyl or a heterocyclicthio(lower)alkyl which may be substituted with suitable substituent(s) and… R<5> is carboxy or a protected carboxy, and… pharmaceutically acceptable salt thereof and process for their preparation, and also a pharmaceutical composition comprising, as an effective ingredient, the above compound in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient. The invention also relates to the starting compounds …<CHEM>… and their preparation.</p> |
申请公布号 |
HU183010(B) |
申请公布日期 |
1984.04.28 |
申请号 |
HU1979FU00370 |
申请日期 |
1979.07.09 |
申请人 |
FUJISAWA PHARMACEUTICAL CO LTD,JP |
发明人 |
TERAJI,TSUTOMU,JP;SAKANE,KAZUO,JP;GOTO,JIRO,JP |
分类号 |
C07D249/12;C07D257/04;C07D285/08;C07D501/20;C07D501/36;(IPC1-7):C07D501/46;C07D501/56 |
主分类号 |
C07D249/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|