发明名称 |
CONSTANT RELEASE RATE SOLID ORAL DOSAGE FORMULATIONS OF DRUGS HAVING A PKA7-10 AND AN AQUEOUS SOLUBILITY OF 15-100G/ML WATER |
摘要 |
A constant order release rate solid oral dosage formulation of verapamil or a pharmaceutically acceptable salt thereof, said formulation comprising: a therapeutically effective amount of verapamil; from about 0.5 to 6.0 weight percent of an acid-retardant or hydrophobic cellulose derivative; from about 2.5 to 35 weight percent of a hydrogenated vegetable oil: from about 1 to 20 weight percent of an acrylic acid polymer; from about 0.5 to 4.0 weight percent of fumed silicon dioxide and from about 0.4 to 3.0 percent of a lubricant. |
申请公布号 |
ZA8306582(B) |
申请公布日期 |
1984.04.25 |
申请号 |
ZA19830006582 |
申请日期 |
1983.09.05 |
申请人 |
VEREX LABOR INC |
发明人 |
DUNN JAMES MICHAEL |
分类号 |
A61K31/13;A61K9/20;A61K9/22;A61K9/26;A61K31/135;A61K31/275;A61K31/445;A61K31/50;A61P7/10;A61P9/04 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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