发明名称 |
DIPYRIDAMOL RETARD-FORMS AND PROCESS FOR THEIR PREPARATION |
摘要 |
This invention relates to a composition for the sustained release of dipyridamole which comprises (i) spheroid particles comprised of dipyridamole or crystallized salts thereof and pharmacologically acceptable acid or acid substance, and (ii) a coating surrounding said spheroid particles, said coating being comprised of from about 50 to 100 percent by weight of acid-insoluble lacquers soluble in intestinal juices and from about 0 to 50 percent by weight of lacquers insoluble in gastric and intestinal juices and said coating being present in an amount of from about 3 to 30 percent by weight, based on the weight of the spheroid particles, and to the preparation of such a composition. |
申请公布号 |
DE3067058(D1) |
申请公布日期 |
1984.04.19 |
申请号 |
DE19803067058 |
申请日期 |
1980.12.17 |
申请人 |
DR. KARL THOMAE GMBH |
发明人 |
GRUBER, PETER, DR. DIPL.-CHEM.;BRICKL, ROLF, DR. DIPL.-CHEM.;BOZLER, GERHARD, DR. DIPL.-CHEM.;STRICKER, HERBERT, PROF. DR. DIPL.-CHEM. |
分类号 |
A61K9/16;A61K9/22;A61K9/24;A61K9/48;A61K9/50;A61K9/52;A61K9/54;A61K9/56;A61K31/505;A61P9/08;A61P9/10 |
主分类号 |
A61K9/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|