摘要 |
<p>An amine compound of formula (I) or an amidine derivative thereof or a pharmaceutically acceptable salt or ester thereof: <CHEM> wherein R<m> is hydrogen or a group -OR, R<n> is hydrogen or methyl, R is hydrogen, -CHO or -SO3H or a pharmaceutically acceptable salt thereof, R<1> and R<2> are independently hydrogen, C1-6 alkyl, or R<1> and R<2> are joined so as to form with the carbon to which they are attached a C3-7 cycloalkyl ring and X<1> and X<2> are independently hydrogen or optionally substituted hydrocarbon; a process for the preparation of such compounds, pharmaceutical compositions comprising them and the intermediates useful in the preparation of the compounds (I).</p> |