发明名称 Antipsychotic 4-(naphthalenyloxy)piperidine derivatives
摘要 Novel compounds of the formula <IMAGE> wherein n is an integer of from 2 to 5, R is hydrogen, alkyl, alkoxy, halogen or trifluoromethyl, R1 is hydrogen, alkyl, alkoxy or halogen, and Z is carbonyl or hydroxymethylene and their pharmaceutically acceptable acid addition salts are useful as antipsychotic agents having a low potential for extrapyramidal side effects. The novel compounds are prepared from novel intermediates of formula <IMAGE> or their salts wherein R has the meanings defined above and R2 is hydrogen, lower alkyl or phenyl(lower alkyl).
申请公布号 US4443462(A) 申请公布日期 1984.04.17
申请号 US19820422819 申请日期 1982.09.24
申请人 MERRELL DOW PHARMACEUTICALS INC. 发明人 CARR, ALBERT A.;FARR, ROBERT A.
分类号 C07D211/46;(IPC1-7):A61K31/44;C07D211/44 主分类号 C07D211/46
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