摘要 |
Cpds. Ph1-A1-Ph2-O-A2-COOH and their functional derivs. esp. esters, amides, nitriles and hydroxamic acids, useful as hypocholesterolaemic, hypolipidaemic and anti-inflammatory agents (where Ph1 is 1,2-phenylene, opt. substd. Ph2 is phenylene opt. substd. A1 is mono- or di-hydroxy-alkylene or alkenylene forming with Ph1 is 5-7 membered ring one of the nuclear atoms of A, being linked to Ph2 and A2 is a bivalent aliphatic group are prepd. by ether formation or reactions wherein the ring contng. A2 is modified or one substituent converted into another). |