| 摘要 |
<p>A process for extracting tumor necrosis factor (TNF) easily and uniformly on a large scale, which comprises collecting macrophage from a living body or multiplying culturable macrophage strain on a large scale, and naturally or artificially killing and destroying them without using any macrophage-stimulating substance (for example, BCG). This process enables extraction of more uniform TNF on a large scale than that obtained by conventional processes using a living body (for example, mouse, rabbit, etc.) and contaminated with much impurities (e.g., albumin, globulin, etc.) </p> |
