| 摘要 |
Compounds of the formula (I), pharmaceutically acceptable salts or N- oxides thereof, and solvates of any of the foregoing: <CHEM> wherein: A is a bond, -CH2- or -CH = CH-; m is 0 or 1; n is 0 to 3; R<4> is C1-4 alkyl or optionally derivatised hydroxy; R<1> is halo, C1-4 alkyl, hydroxy, C1-4 alkanoyl, nitro, cyano, CF3 or amino optionally substituted by one or two C1-4 alkyl groups; and R<2> and R<3> are each independently halo, C1-4 alkyl, or hydroxy; and L is 1-pyrrolidyl, 1-piperidyl, 1-morpholinyl or 4-methyl-1-piperazyl, optionally singly substituted as appropriate by a methyl group at each carbon atom in the 2-, 4- or 6-position up to a total of two methylsubstituents in the radical L, pharmaceutical compositions containing them, a process for their preparation, and intermediates for their preparation, and the compounds for therapeutic or prophylactic use. |
