CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

Cephalosporins of the formula (I) wherein Y is hydrogen or methoxy, A is optionally substituted aminothiazolyl, phenyl, 4-hydroxyphenyl, 3,4-dihydroxy-phenyl or thienyl; D is hydrogen, acetoxy, aminocarbonyloxy, pyridinium, aminocarbonylpyridinium, substituted triazin-3-ylthio or 1-substituted-tetrazol-5-ylthio; and R2 is optionally substituted heterocyclyl or heterocyclylmethyl; and E is hydrogen or a protecting group; as well as tautomers and salts thereof. The novel compounds may be prepared by a variety of processes, and formed into pharmaceutical compositions. The compounds possess antibacterial activity.