| 摘要 |
Pyrazoloquinolines I and II (R=optionally substituted Ph, pyridyl; R1=H, optionally substituted alkyl; R2=H, alkyl) and some related compds. were prepd. for use as tranquilizers and antidepressants (no data). Thus, EtOCH:C(CO2Et)2 reacted with PhNH2 to give PhNHCH:C(CO2Et)2, Which was thermally cyclized to Et 4-hydroxy-3-quinolinecarboxylate (III). Chlorination of III and reaction with 4-ClC6H4NHNH2 gave II (R=4-ClC6H4; R1=R2=H), which was converted to II [R=4-ClC6H4;R1=Me, (CH2)3NMe2; R2=H . |
