摘要 |
<p>Procedure for producing 2-aminopyridines having general formula: <IMAGE> from 2-pyridine carboxylic acid-N-oxides having the formula: <IMAGE> wherein R is H or a -COOH group or an alkyl group having C1 to C8 or an aryl group, and n is a number between 1 and 4. The 2-pyridine carboxylic acid-N-oxide is converted with a lower aliphatic carboxylic acid anhydride and a tertiary amine in the presence of a carboxylic acid nitrile. The conversion product is hydrolyzed to the 2-aminopyridine compound.</p> |