| 摘要 |
<p>Cephalosporins (I; R=H, Me, cyclopropyl, OH, OMe, OEt, SH, amino; A=optionally substituted Ph, cyclohexyl, 1-cyclohexenyl, 2,4-cyclohexadienyl, thienyl, furyl; D=H, OH, OAc, O2CNH2, pyridinium, carbamoylpyridinium, heterocyclylthio; E=H, protective group) were prepd. Thus, diphenylmethyl-7-β-{D-α-[(4-hydroxy-2-p-methyl-aminosulfonylanilino-5-pyrimidinyl)ureido -p-hydroxyphenylacetamido}-3-[(1-methyltetrazol-5-yl)thiomethyl -ceph-3-em-4-carboxylate was treated with MeOH, chloroform, and LiOCH3 to give its Na-salt.</p> |
