发明名称 |
NON A, NON B HEPATITIS VIRUS, METHODS OF IDENTIFICATION, PURIFICATION, CHARACTERIZATION, DIAGNOSIS AND IMMUNIZATION |
摘要 |
<p>A purified form of a DNA virus which has the following characteristics: molecular weight greater than 2 X 10<6> Daltons; substantial immunoreactivity towards an anti-HBsAg monoclonal antibody 5D3; substantially no immunoreactivity towards an anti-HBsAg monoclonal antibody obtained from cell line ATCC CRL 8018; concentration dependent immunoreactivity towards polyclonal IgG anti-HBsAg antibodies, which increases with increased concentration of said DNA virus; discrete particulate form when observed by immunoelectron microscopy in the presence of IgM antibodies from cell line ATCC HB 8058; the DNA of said virus showing hybridization with DNA from hepatitis B viral DNA; and said DNA virus showing, in chimpanzees, infectivity having the characteristics of non A, non B hepatitis.</p> |
申请公布号 |
WO8401107(A1) |
申请公布日期 |
1984.03.29 |
申请号 |
WO1983US01412 |
申请日期 |
1983.09.16 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
WANDS, JACK;SHAFRITZ, DAVID, A. |
分类号 |
C12N7/00;A61K39/29;C12N7/04;C12Q1/70;G01N33/576;(IPC1-7):61K39/29;12N7/00;12N7/02;01N33/54 |
主分类号 |
C12N7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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