Phosphate derivatives, process for preparation thereof and pharmaceutical compositions of the same.

摘要

New phosphate derivatives represented by the formula: <CHEM> wherein R<1>, R<2>, and R<3> are each hydroxy, alkoxy, alkanoylamino or protected hydroxy; A is lower alkylene; R<4> is alkylammonio, cyclic ammonio or cyclic amino; and R<5> is oxido anion or hydroxy; and pharmaceutically acceptable salt thereof, which exhibit antitumor activity