发明名称 TESTOSTERONE-5ALPHA-REDUCTASE INHIBITOR
摘要 PURPOSE:To provide the titled inhibitor free from the hormone-like action, applicable externally and safely for a long period, and useful for the prevention of the symptoms such as male pattern baldness, by using 4-methyl-1-isopropyl- bicyclo[3,1,0]hexen-3-one-2 and/or a specific compound as an active component. CONSTITUTION:The objective inhibitor contains 4-methyl-1-isopropyl-bicyclo-[3, 1,0]hexen-3-one-2 of formula I and/or 4,6,6-trimethylbicyclo[3,1,1]hepten-3-one-2 of formula II as an active component. The compound of formula I is a terpenic ketone obtained from American laurel, and the compound of formula II is a terpene ketone obtained from Verbena officinalis, etc. Both compounds have absolutely no hormone-like action, and are free of undersirable side effects.
申请公布号 JPS5953419(A) 申请公布日期 1984.03.28
申请号 JP19820164277 申请日期 1982.09.21
申请人 SHISEIDO KK 发明人 NISHIYAMA TOSHIO;HIRAMA SHINICHI;UZUKA MAKOTO;NAKAJIMA KEISUKE;TOMITA KENICHI;NAKAMURA SHIYOUJI
分类号 A61K31/12;A61K8/00;A61K8/35;A61P17/00;A61P43/00;A61Q5/00;A61Q7/00;C12N9/99 主分类号 A61K31/12
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