| 摘要 |
Mildiomycin is produced by fermn. with Streptoverticillium rimofaciens. Thus, one loopful of s. rimofaciens FERM-P2549 (IFO 13592) was inoculated into 25mL medium contg. glucose 10%, Proflo 3%, corn ext. soln. 1%, NaCl 0.5%, FeSO4 0.001%, CaCO3 0.5%, and choline 3-70mM and incubated in rotary shaker (200rpm) at 28≦̸C fro 120hr. The broth (1 L) was filtered, treated with anion exchange chromatog., and concd. After addn. of MeOH to the conc., 1.1g mildiomycin was obtained. Mildiomycin inhibited the powder milew and has acaricidal properties.
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