发明名称 |
Crystalline forms of addition salts with acids, of ((amino-2-thiazolyl-4)-2-methoxyimino-2-acetamido)-7-carboxy-2-((dioxo-5,6-formylmethyl-4-tetrahydro-1,4,5,6-triazine-1,2,4-yl-3)-thio-2-vinyl)-33-oxo-8-thia-5-aza-1-bicyclo(4.2.0)-octene-2-isomer syn, form E and their preparation. |
摘要 |
<p>Crystalline forms of addition salts with trifluoroacetic, methanesulphonic or hydrochloric acid, of the E form syn isomer of 7-[2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-2-carboxy-3- [(5,6-dioxo-4-formylmethyl-1,4,5,6-tetrahydro-1,2,4-triazin-3-yl)-2- thiovinyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]-2-octene of formula: <IMAGE> and their preparation. These salts are useful for the purification of the above product and for use in pharmacy.</p> |
申请公布号 |
EP0102896(A1) |
申请公布日期 |
1984.03.14 |
申请号 |
EP19830401698 |
申请日期 |
1983.08.23 |
申请人 |
RHONE-POULENC SANTE |
发明人 |
BERGER, CHRISTIAN;FARGE, DANIEL;LE ROY, PIERRE;MOUTONNIER, CLAUDE |
分类号 |
C07D501/00;A61K;A61K31/545;C07D;C07D501/24;C07D501/46;(IPC1-7):07D501/24 |
主分类号 |
C07D501/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|