发明名称 Crystalline forms of addition salts with acids, of ((amino-2-thiazolyl-4)-2-methoxyimino-2-acetamido)-7-carboxy-2-((dioxo-5,6-formylmethyl-4-tetrahydro-1,4,5,6-triazine-1,2,4-yl-3)-thio-2-vinyl)-33-oxo-8-thia-5-aza-1-bicyclo(4.2.0)-octene-2-isomer syn, form E and their preparation.
摘要 <p>Crystalline forms of addition salts with trifluoroacetic, methanesulphonic or hydrochloric acid, of the E form syn isomer of 7-[2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-2-carboxy-3- [(5,6-dioxo-4-formylmethyl-1,4,5,6-tetrahydro-1,2,4-triazin-3-yl)-2- thiovinyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]-2-octene of formula: &lt;IMAGE&gt; and their preparation. These salts are useful for the purification of the above product and for use in pharmacy.</p>
申请公布号 EP0102896(A1) 申请公布日期 1984.03.14
申请号 EP19830401698 申请日期 1983.08.23
申请人 RHONE-POULENC SANTE 发明人 BERGER, CHRISTIAN;FARGE, DANIEL;LE ROY, PIERRE;MOUTONNIER, CLAUDE
分类号 C07D501/00;A61K;A61K31/545;C07D;C07D501/24;C07D501/46;(IPC1-7):07D501/24 主分类号 C07D501/00
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