MONO(2-AMMONIUM-2-HYDROXYMETHYL-1,3-PROPANEDIOL) (2R-CIS)-(3-METHYLOXIRANYL) PHOSPHONATE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

摘要

Mono(2-ammonium-2-hydroxymethyl-1,3-propanediol)(2R-cis)- (3-methyloxiranyl)phosphonate endowed with therapeutic activity as broad-spectrum antibiotic, as well as a method for preparing same from bis(2-ammonium-2-hydroxymethyl-1, 3-propanediol)(2R-cis)-(3-methyloxiranyl)phosphonate and a sulphonic acid. Pharmaceutical compositions containing the novel mono(2ammonium-2-hydroxymethyl-1,3-propanediol)(2R-cis)-(3-methyloxiranyl)phosphonate are also disclosed.