| 摘要 |
The present invention relates to new pharmacodynamically active compounds of the general structure <IMAGE> I as well as the corresponding amine oxides, quarternary ammonium compounds and salts with physiologically acceptable acids. In formula I R1 signifies hydrogen, halogen or alkoxy radicals having 1-3 carbon atoms, R2 and R3 signify alkyl radicals having 1-3 carbon atoms, which togetner with the carbon atom, to which they are connected, may form a ring, A either signifies a possibly lower alkyl substituted ethylene, trimethylene or tetramethylene group, in which case D is a group <IMAGE> wherein R4 and R5 individually signify hydrogen or alkyl groups having 1-4 carbon atoms, or together with the nitrogen atom form a heterocyclic ring, which in addition to said nitrogen atom may contain an oxygen atom or possibly lower alkylated amino group, or A and B taken together signify a piperidino- or N-lower alkylpiperidino group, which is connected to an indene residue in 4-position, and the broken lines signify a double bond in either endo- or exo position. |
