发明名称 2-(o-Carboxyphenylamino)-6H-pyrimido[2,1-b]-6-quinazolone and its derivatives, process for its preparation and compositions which contain these compounds
摘要 2-(o-Carboxyphenylamine)-6H-pyrimido[2,1-b]-6-quinazolone having the following structural formula: <IMAGE> derivatives of 2-(o-carboxyphenylamino)-6H-pyrimido[2,1-b]- 6-quinazolone having the following structural formula: <IMAGE> in which A<+> denotes alkali metals, monoethanolamine or diethylamine, derivatives of 2-(o-carboxyphenylamino)-6H-pyrimido[2,1-b]- 6-quinazolone having the following structural formula: <IMAGE> in which R represents -OH, C1 to C4 alkoxy, NHR' where R' represents -H, C1 to C4 alkyl, phenyl or aralkyl and A represents inorganic acid, and also derivatives of 2-(o-carboxyphenylamino)-6H-pyrimido[2,1-b]- 6-quinazolone with the following structural formula: <IMAGE> in which R denotes C1 to C4 alkoxy or NHR' where R' denotes C1 to C4 alkyl, are described. A process for the preparation of the compounds according to the invention and medicaments which contain them are additionally disclosed.
申请公布号 DE3231408(A1) 申请公布日期 1984.03.01
申请号 DE19823231408 申请日期 1982.08.24
申请人 KIEVSKIJ NAUCNO-ISSLEDOVATEL'SKIJ INSTITUT FARMAKOLOGII I TOKSIKOLOGII 发明人 ALEKSANDROVNA PORTNYAGINA,VERA;KUPRIYANOVNA KARP,VALENTINA;STEPANOVNA BARKOVA,IRINA;PETROVIC TRINUS,FEDOR;ANTONOVIC MOCHORT,NIKOLAI;GEORGIEVNA FADEICEVA,ALEKSANDRA;ILINICHNA KOZUSKO,GALINA;KIRILLOVNA RYABUCHA,TATYANA;GAVRILOVIC PANTELEIMONOV,ALEKSANDR;VASILIEVIC KLJUSIN,VIKTOR;NIKOLAEVIC DOBROVOLSKY,JURIJ;MICHAILOVNA KIRICEK,LARAISA;ALEKSANDROVIC MEDVEDOVSKY,ADOLF;ALEKSANDROVNA GETMAN,GALINA;DMITRIEVIC USENKO,JURIJ;MICHAILOVIC SIDELNIKOV,VIKTOR;FEDOROVIC DANILEVSKY,NIKOLAI;PORFIRIEVIC SOLSKY,YAKOV
分类号 C07D487/04;(IPC1-7):C07D487/04;A61K31/50 主分类号 C07D487/04
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