发明名称 |
Improved protocol for the treatment of graft versus host disease. |
摘要 |
<p>This invention relates to a monoclonal antibody known as TA-1 directed against human T-cells and which is covalently linked to the toxin ricin and used to treat human donor bone marrow before the marrow is infused into a human recipient. Additionally, monoclonal antibodies known as TA-1, T101, and UCHT1 covalently linked to separate ricin toxins, are combined in a mixture and used in an improved protocol in the treatment of human donor bone marrow prior to the infusion of the marrow into a human recipient. </p> |
申请公布号 |
EP0100904(A2) |
申请公布日期 |
1984.02.22 |
申请号 |
EP19830106912 |
申请日期 |
1983.07.14 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY UNITED STATES DEPARTMENT OF COMMERCE |
发明人 |
NEVILLE, DAVID M., JR.;YOULE, RICHARD J. |
分类号 |
A61K39/00;A61K38/00;C07K14/00;C07K16/00;C07K16/28 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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