N-CYANOALKYL HALOCETAMIDES HERBICIDAL ANTIDOTES

摘要

Haloalkanoyl halides reacted with amino nitriles to yield RCONR1R2 (R=haloalkyl; R1=H, alkyl; R2=cyanoalkyl, cyanoalkylcycloalkyl, cyanocycloalkyl, cyanobenzyl), which showed their effectiveness as herbicide antidotes. Thus, BrCH2CHBrCOCl in CH2Cl2 was treated with Me2CHC(NH2)MeCNHCl and NaOH in CH2Cl2-water to give BrCH2CHBrCONHC(CN) ! MeCHMe2.