FORFARANDE FOR FRAMSTELLNING AV EN KRISTALLINFORM AV FLUNISOLID (6ALFA-FLUOR-11BETA,21-DIHYDROXI-16ALFA,17ALFA-ISOPROPYLIDENDIOXIPREGNA-1,4-DIEN-3,20-DION)

摘要

A unique crystalline form of flunisolide is prepared by crystallizing flunisolide from a solution thereof in an alkanol of three or four carbon atoms, e.g. n-butanol, containing 0.2 to 5%, preferably 1.0 to 4.0% by volume water.