| 摘要 |
Cpds. of formula (I) and their salts when X is S are new:- X=S or -S(O)-; R15=H, CH3 or C2H5; R1, R2, R3, R4=same or different H, halo, CN, -CHO, CF3, -COR'', -CH(OR13)2, -(Z)n-A-D, aryl, aryloxy, 1-6C alkylthio, NO2, 1-6C alkylsulphinyl or adjacent gps. R1, R2, R3, R4 together form a 5,6 or 7 membered monocyclic ring or 9, 10 or 11 membered bicyclic Mg both opt. unsatd. and opt. contg. 0 to 3 of N and/or O fused to the benzimidazole ring. R11 and R12=same or different aryl, 1-4C alkoxy, 1-3C alkoxy (1-3C) alkoxy, aryl (1-2C) alkoxy, aryloxy, di(1-3C)alkylamino, pyrrolidino or piperidino both opt. substd. by 1-3C alkyl; R13=1-4C alkyl or 2-3C alkylene; Z=-O- or -C(=O)-; L=0 or 1; A=1-6C alkylene, 3-6C cycloalkylene, 2-6C alkylene, 3-6C cycloalkylene or 2-6C alkynylene; D=CN, -C(=O)R9, -(Y)m-(C=O)r-R16; R9=1-5C alkoxy or di(1-3C)alkylamino; m=O or 1; r=O or 1; y=-O-, -NH-, -NR10-; R10=H, 1-3C alkyl, aryl(1-2C) alkyl or aryl; R5=H or -CO-R14; R14=1-6C alkyl, aryl(1-2C) alkyl, aryl, 1-4C alkoxy, aryl(1-2C) alkyl, aryloxy, amino, mono- or di-(1-4C) alkylamino, aryl(1-2C) alkylamino or arylamino; R6 and R8=same or different H, or 1-5C alkyl; R7=1-8C alkyl, 1-8C alkoxy, 2-5C alkenyloxy, 2-5C alkynyloxy, 1-2C alkoxy (1-2C) alkoxy, di(1-2C) alkylamino (1-4C) alkoxy, 3-7C oxacycloalkyl, 4-7C oxacycloalkoxy, 4-7C oxacycloalkylalkyl, 4-6C oxacycloalkylalkoxy R6 and R7 or R7 and R8 together with the adjacent carbon atoms in the pyridine form a ring where R6 and R7 or R7 and R8 is -CH=CH-CH=CH-, -O-(CH2)p-, -CH2(CH2)p-, -O-CH=CH-, -NH-CH=CH- or -N(CH3)CH=CH- p=2,3 or 4.(0/0) |
